JUP antibody (AA 732-745)
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- Target See all JUP Antibodies
- JUP (Junction Plakoglobin (JUP))
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Binding Specificity
- AA 732-745
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Reactivity
- Human, Mouse, Dog, Rabbit, Monkey, Hamster
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This JUP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Human JUP / Gamma Catenin. This antibody is expected to recognise both reported isoforms, as represented by NP_002221.1 and NP_068831.1.
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Dog, Hamster, Panda, Rabbit (100%) Rat, Bat, Bovine, Pig, Opossum (93%) Elephant (86%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-GLRPPYPTADHMLA from the C-terminus of human JUP / Gamma Catenin (NP_002221.1, NP_068831.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Dog, Hamster, Panda, Rabbit (100%), Rat, Bat, Bovine, Pig, Opossum (93%), Elephant (86%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product JUP Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000), WB (0.2 - 1 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- JUP (Junction Plakoglobin (JUP))
- Alternative Name
- JUP/CTNNG/Junction Plakoglobin (JUP Products)
- Synonyms
- ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
- Background
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Name/Gene ID: JUP
Family: Catenin
Synonyms: JUP, Desmoplakin-3, CTNNG, DPIII, Gamma catenin, Junction plakoglobin, PKGB, ARVD12, Catenin gamma, Desmoplakin III, DP3, PDGB - Gene ID
- 3728
- NCBI Accession
- NP_002221, NP_068831
- UniProt
- P14923
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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