IL1R1 antibody (Extracellular Domain)
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- Target See all IL1R1 Antibodies
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL1R1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Radioimmunoassay (RIA)
- Specificity
- Reacts with cell surface and soluble human IL-1 receptor, Specific epitopes are unknown, but it does partially inhibit (30-50 % ) binding of one another to IL-1 receptor. Does not block binding of IL-1 to receptor, and does not cross-react with receptors for human IL-2 or IL-4.
- Purification
- Protein G purified
- Immunogen
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The extracellular domain of the type I human IL-1 receptor.
Type of Immunogen: Protein - Isotype
- IgG2b
- Top Product
- Discover our top product IL1R1 Primary Antibody
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- Application Notes
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Approved: ELISA (10 - 100 μg/mL), IHC, RIA
Usage: ELISA: Can be used as capture reagents or second antibody at a concentration of 5 μg/mL. RIA: Concentrations of 20-30 ng/mL of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunohistochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Alternative Name
- IL1RA / IL1R1 (IL1R1 Products)
- Synonyms
- CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
- Background
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Name/Gene ID: IL1R1
Family: Interleukin
Synonyms: IL1R1, Antigen CD121a, D2S1473, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL1R, IL1RA, IL1RT1, Interleukin receptor 1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, CD121A, CD121a antigen, Interleukin 1 receptor, type I, Interleukin-1 receptor type I, Interleukin-1 type i receptor, p80 - Gene ID
- 3554
- UniProt
- P14778
- Pathways
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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