Aromatase antibody (AA 475-486)
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- Target See all Aromatase (CYP19A1) Antibodies
- Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
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Binding Specificity
- AA 475-486
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Aromatase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Human CYP19A1 / Aromatase. This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (92%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-HDLSLHPDETKN from an internal region of human CYP19A1 / Aromatase (NP_000094.2, NP_112503.1). Percent identity by BLAST analysis: Human, Gorilla (100%), Gibbon, Monkey (92%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product CYP19A1 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (4 μg/mL), Peptide-ELISA (1:128000), WB (0.1 - 0.3 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 4 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
- Alternative Name
- CYP19 / Aromatase (CYP19A1 Products)
- Synonyms
- ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, CYPXIX antibody, P-450AROM antibody, Aromatase antibody, Cyp19 antibody, Cyp19a antibody, p450arom antibody, P450 arom antibody, aro antibody, cyp19 antibody, cyp19a antibody, p450arom-A antibody, P450AROM antibody, Ar antibody, ArKO antibody, Int-5 antibody, Int5 antibody, CYP19P1 antibody, CYP19A1 antibody, CYP19a1 antibody, P450aromA antibody, ar1 antibody, cypXIX antibody, etID309862.18 antibody, zgc:136541 antibody, AroB antibody, CYP19a2 antibody, P450aromB antibody, cyp19b antibody, zgc:92614 antibody, cyp19a1 antibody, cytochrome P450 family 19 subfamily A member 1 antibody, cytochrome P450, family 19, subfamily a, polypeptide 1 antibody, cytochrome P450 family 19 subfamily A member 1 L homeolog antibody, aromatase antibody, cytochrome P450 aromatase antibody, cytochrome P450, family 19, subfamily A, polypeptide 1 antibody, cytochrome P450 19A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, cytochrome P450, family 19 antibody, cytochrome P450, family 19, subfamily A, polypeptide 1a antibody, cytochrome P450, family 19, subfamily A, polypeptide 1b antibody, cytochrome P450 19A1-like antibody, CYP19A1 antibody, Cyp19a1 antibody, cyp19a1.L antibody, SAV_2383 antibody, pfcyp19b-tstr antibody, CYP19 antibody, cyp19a1a antibody, cyp19a1b antibody, LOC101174651 antibody
- Background
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Name/Gene ID: CYP19A1
Family: Cytochrome P450
Synonyms: CYP19A1, ARO1, CYAR, CPV1, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, CYP19, Estrogen synthase, Estrogen synthetase, P-450AROM, ARO, Aromatase - Gene ID
- 1588
- NCBI Accession
- NP_000094, NP_112503
- UniProt
- P11511
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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