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APH1A antibody (Internal Region)

APH1A Reactivity: Human, Mouse, Rat WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374764
  • Target See all APH1A Antibodies
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    Binding Specificity
    • 16
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 51
    • 35
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 56
    • 1
    Goat
    Clonality
    • 57
    Polyclonal
    Conjugate
    • 21
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APH1A antibody is un-conjugated
    Application
    • 48
    • 33
    • 14
    • 13
    • 13
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to APH1A.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-HVTDRSDARLQYG, from the internal region of the protein sequence
    Top Product
    Discover our top product APH1A Primary Antibody
  • Application Notes
    Peptide ELISA: 1/128000. Western Blot: 0.05 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    Alternative Name
    APH1A (APH1A Products)
    Synonyms
    6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
    Background
    Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).Synonyms: APH-1A, Aph-1 alpha, CGI-78, Gamma-secretase subunit APH-1A, PSF, Presenilin-stabilization factor
    Gene ID
    51107, 9606
    UniProt
    Q96BI3
    Pathways
    Notch Signaling, Neurotrophin Signaling Pathway
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