IL-1 beta antibody
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- Target See all IL-1 beta (IL1B) Antibodies
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-1 beta antibody is un-conjugated
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Application
- Enzyme Immunoassay (EIA)
- Specificity
- Reactive with natural and recombinant Human Interleukin-1 beta (IL1 beta). Does not show any cross reaction with recombinant Human IL1 alpha, recombinant Murine IL1 alpha or IL1 beta.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity Chromatography on Protein G.
- Immunogen
- Purified recombinant Human IL1 beta.
- Clone
- S1B7
- Isotype
- IgG1
- Top Product
- Discover our top product IL1B Primary Antibody
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- Application Notes
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with double distillated water to adjust the final concentration to 1.00 mg/mL
- Concentration
- 1.0 mg/mL
- Buffer
- 0.01 M PBS, pH 7.2 without preservatives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer.
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- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Alternative Name
- Interleukin-1 beta / IL-1B (IL1B Products)
- Synonyms
- IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
- Background
- Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
- Gene ID
- 3553
- NCBI Accession
- NP_000567
- UniProt
- P01584
- Pathways
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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