CD11b antibody
-
- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CD11b antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
- Specificity
- Reacts with human Integrin alpha-M
- Purification
- Purified (protein A)
- Immunogen
- recombinant human GST-Integrin alpha-M protein
- Top Product
- Discover our top product ITGAM Primary Antibody
-
-
- Application Notes
-
Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000) ICC/IF(1:200 - 1:1000) - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M
- Storage
- 4 °C/-20 °C
- Storage Comment
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 6 months
-
- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- Integrin alpha-M (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
- Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
- Gene ID
- 3684
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
-