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CD11b antibody

ITGAM Reactivity: Human WB, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4889291
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 251
    • 160
    • 62
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Human
    Host
    • 132
    • 102
    • 95
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 235
    • 96
    • 1
    Polyclonal
    Conjugate
    • 112
    • 37
    • 29
    • 25
    • 19
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is un-conjugated
    Application
    • 248
    • 81
    • 76
    • 70
    • 56
    • 36
    • 36
    • 25
    • 20
    • 19
    • 13
    • 13
    • 7
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    • 3
    • 2
    • 2
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    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    Specificity
    Reacts with human Integrin alpha-M
    Purification
    Purified (protein A)
    Immunogen
    recombinant human GST-Integrin alpha-M protein
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    Discover our top product ITGAM Primary Antibody
  • Application Notes

    Working dilution: Optimal dilutions should be determined by the end user.
    The following are guidelines only:
    WB(1:500 - 1:2000) ICC/IF(1:200 - 1:1000)

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Concentration
    1 mg/mL
    Buffer
    Tris 0,1M, glycine 0,1M
    Storage
    4 °C/-20 °C
    Storage Comment
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Expiry Date
    6 months
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    Integrin alpha-M (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
    Gene ID
    3684
    UniProt
    P11215
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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