GABRB2 antibody (AA 449-462)

Catalog No. ABIN490402

Product Details anti-GABRB2 Antibody

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Binding Specificity: AA 449-462

Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Pig, Chicken, Monkey, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is un-conjugated

Application: ELISA

Specificity: Human GABRB2. This antibody is expected to recognize both reported isoforms (NP_068711.1, NP_000804.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard (100%) Bat, Zebrafish (93%) Xenopus (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-HSFGRNALERHVAQ from an internal region of human GABRB2 (NP_068711.1, NP_000804.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard (100%), Bat, Zebrafish (93%), Xenopus (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:4000)

Usage: Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Preliminary experiments gave an approx 80  kDa band in Mouse Brain lysates after 0.2 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 59.2  kDa according to Human NP_068711.1 and 54.6  kDa according to Mouse NP_032096.1. The 80  kDa band was successfully blocked by incubation with the immunizing peptide.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABRB2 (GABRB2 Products)

Synonyms: GABRB2 antibody, GARB2 antibody, fj59e04 antibody, gabaabeta2 antibody, wu:fj59e04 antibody, zgc:136311 antibody, GABARB antibody, AI834970 antibody, C030002O17Rik antibody, C030021G16Rik antibody, Gabrab2 antibody, Gabrb-2 antibody, gamma-aminobutyric acid type A receptor beta2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 2 antibody, gamma-aminobutyric acid type A receptor beta 2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 antibody, GABRB2 antibody, gabrb2 antibody, Gabrb2 antibody

Background: Name/Gene ID: GABRB2
Subfamily: GABA A receptor
Family: Ion Channel

Synonyms: GABRB2, GABA A receptor beta 2, GABA(A) receptor, beta 2

Gene ID: 2561

NCBI Accession: NP_068711, NP_000804

UniProt: P47870

Pathways: Sensory Perception of Sound, Synaptic Membrane