NLRP2 antibody (AA 1037-1050)

Catalog No. ABIN490691

Product Details anti-NLRP2 Antibody

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Binding Specificity: AA 1037-1050

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NLRP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human NLRP2 / NALP2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KNPQLIIDTEKHHP from the C-terminus (near) of human NLRP2 / NALP2 (NP_060322.1). Percent identity by BLAST analysis: Human, Gorilla (100%), Gibbon, Monkey (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 140  kDa band observed in lysates of cell line K562 (calculated MW of 121  kDa according to NP_060322.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Alternative Name: NLRP2 / NBS1 (NLRP2 Products)

Synonyms: CLR19.9 antibody, NALP2 antibody, NBS1 antibody, PAN1 antibody, PYPAF2 antibody, NLRP2 antibody, E330007A02Rik antibody, Nalp2 antibody, NLR family pyrin domain containing 2 antibody, NACHT, LRR and PYD domains-containing protein 2 antibody, NLR family pyrin domain containing 7 antibody, NLR family, pyrin domain containing 2 antibody, NLRP2 antibody, LOC100301026 antibody, LOC100387349 antibody, NLRP7 antibody, Nlrp2 antibody

Background: Name/Gene ID: NLRP2

Synonyms: NLRP2, CLR19.9, PAN1, NALP2, NBS1, PYPAF2

Gene ID: 55655

NCBI Accession: NP_060322

UniProt: Q9NX02

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome