MBD3 antibody (C-Term)
-
- Target See all MBD3 Antibodies
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse, Rat, Monkey, Hamster
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MBD3 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)
- Purification
- Purified (protein A)
- Immunogen
- Synthetic peptide of derived from C terminal part of human MBD3.
- Top Product
- Discover our top product MBD3 Primary Antibody
-
-
- Application Notes
-
Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M
- Storage
- 4 °C/-20 °C
- Storage Comment
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 6 months
-
- Target
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Alternative Name
- MBD3 (MBD3 Products)
- Synonyms
- xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
- Background
- Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
- Gene ID
- 53615
- UniProt
- O95983
- Pathways
- Chromatin Binding
-