c-MYC antibody (AA 40-69)

Catalog No. ABIN3029538

The Rabbit Polyclonal anti-c-MYC antibody (ABIN3029538) specifically detects c-MYC in WB, FACS and ELISA. The antibody is reactive with Human samples.

Quick Overview for c-MYC antibody (AA 40-69) (ABIN3029538)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-MYC antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-c-MYC Antibody

Binding Specificity: AA 40-69

Purpose: Anti-Myc Antibody

Predicted Reactivity: Bovine,Mouse,Pig,Rat

Purification: Antigen affinity

Immunogen: A portion of amino acids 40-69 from the human protein was used as the immunogen for this anti-Myc antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the anti-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: Myc

Background: MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.

UniProt: P01106

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect