COPS5 antibody

Catalog No. ABIN498350

Product Details anti-COPS5 Antibody

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of JAB1 protein. (region surrounding Lys191)

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for COPS5

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Alternative Name: COPS5 (COPS5 Products)

Synonyms: BcDNA.LD14392 antibody, BcDNA:LD14392 antibody, CG14884 antibody, CH5 antibody, CSN-5 antibody, Csn5 antibody, DCH5 antibody, Dch5 antibody, Dmel\\CG14884 antibody, JAB1 antibody, JAB1/CSN5 antibody, Jab1 antibody, JadBp antibody, csn5 antibody, dch5 antibody, jab1/csn5 antibody, l(3)89Cf antibody, l(3)L4032 antibody, l(3)M203 antibody, quo antibody, COPS5 antibody, MGC76063 antibody, AI303502 antibody, CSN5 antibody, Mov34 antibody, Sgn5 antibody, zgc:73130 antibody, MOV-34 antibody, SGN5 antibody, COP9 signalosome subunit 5 antibody, COP9 signalosome complex subunit 5 antibody, COP9 signalosome subunit 5 S homeolog antibody, CSN5 antibody, COPS5 antibody, cops5 antibody, CpipJ_CPIJ012314 antibody, Bm1_46585 antibody, VDBG_06932 antibody, LOAG_01443 antibody, csn5 antibody, Cops5 antibody, cops5.S antibody, csn-5 antibody

Background: Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, but the Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.Synonyms: COP9 signalosome complex subunit 5, CSN5, JAB1, Jun activation domain-binding protein 1, SGN5, Signalosome subunit 5

Molecular Weight: approx. 38 kDa

Gene ID: 10987

NCBI Accession: NP_006828

UniProt: Q92905

Pathways: Cell Division Cycle