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SOCS1 antibody
SOCS1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SOCS1 Antibody
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Target
See all SOCS1 Antibodies
SOCS1
(Suppressor of Cytokine Signaling 1 (SOCS1))
Reactivity
All reactivities for SOCS1 antibodies
Human, Mouse, Rat
Host
All hosts for SOCS1 antibodies
Rabbit
Clonality
All clonalities for SOCS1 antibodies
Polyclonal
Conjugate
All conjugates for SOCS1 antibodies
This SOCS1 antibody is un-conjugated
Application
All applications for SOCS1 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of SOCS1 / JAB protein. (region surrounding Val98)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography using epitope-specific immunogen
Purity
> 95 % (by SDS-PAGE)
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Alternatives
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Application Details
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Application Notes
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for SOCS1
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Target
SOCS1
(Suppressor of Cytokine Signaling 1 (SOCS1))
Alternative Name
SOCS1 (SOCS1 Products )
Synonyms
socs1 antibody, zgc:91868 antibody, jab antibody, cis1 antibody, ssi1 antibody, tip3 antibody, cish1 antibody, ssi-1 antibody, socs-1 antibody, SOCS1 antibody, LOC100228306 antibody, socs1b antibody, CIS1 antibody, CISH1 antibody, JAB antibody, SOCS-1 antibody, SSI-1 antibody, SSI1 antibody, TIP3 antibody, Cish1 antibody, Cish7 antibody, Socs-1 antibody, suppressor of cytokine signaling 1a antibody, suppressor of cytokine signaling 1 antibody, suppressor of cytokine signaling 1 L homeolog antibody, socs1a antibody, socs1 antibody, SOCS1 antibody, socs1.L antibody, Socs1 antibody
Background
The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
Molecular Weight
approx. 38 kDa
Gene ID
8651
NCBI Accession
NP_003736
UniProt
O15524
Pathways
JAK-STAT Signaling , Interferon-gamma Pathway , TLR Signaling , Response to Growth Hormone Stimulus
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