TNFRSF10B antibody (Isoform 2)

Catalog No. ABIN537308

Product Details anti-TNFRSF10B Antibody

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Binding Specificity: AA 388-407, Isoform 2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purpose: Rabbit polyclonal antibody raised against partial recombinant TNFRSF10B.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to amino acids 388-407 (isoform 2) of human TNFRSF10B.

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TNFRSF10B antibody (ABIN537308)

Kusaba, Nakao, Goto, Nishimura, Kawashimo, Shibata, Motoyoshi, Taura, Ichikawa, Hamasaki, Eguchi: "Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis." in: Journal of hepatology, Vol. 47, Issue 4, pp. 546-55, (2007) (PubMed).

Abdelrahim, Newman, Vanderlaag, Samudio, Safe: "3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5." in: Carcinogenesis, Vol. 27, Issue 4, pp. 717-28, (2006) (PubMed).

Younes, Georgakis, Rahmani, Beer, Younes: "Functional expression of TRAIL receptors TRAIL-R1 and TRAIL-R2 in esophageal adenocarcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 42, Issue 4, pp. 542-7, (2006) (PubMed).

Song, Bellail, Tse, Yong, Hao: "Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 12, pp. 3299-308, (2006) (PubMed).

Xu, Zhou, Wu: "Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy." in: Cancer research, Vol. 66, Issue 20, pp. 10092-9, (2006) (PubMed).

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: CD262 / TRAILR2 (TNFRSF10B Products)

Synonyms: TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody

Gene ID: 8795

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity