DIO3 antibody (AA 250-300)

Catalog No. ABIN540383

Product Details anti-DIO3 Antibody

Target: DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))

Binding Specificity: AA 250-300

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Dio3.

Cross-Reactivity: Mouse, Rat

Immunogen: A synthetic peptide corresponding to amino acids 250-300 of rat Dio3.

Application Details

Application Notes: Western Blot (0.5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-DIO3 antibody (ABIN540383)

Baqui, Botero, Gereben, Curcio, Harney, Salvatore, Sorimachi, Larsen, Bianco: "Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes." in: The Journal of biological chemistry, Vol. 278, Issue 2, pp. 1206-11, (2003) (PubMed).

Huang, Dorfman, Genest, Salvatore, Larsen: "Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 3, pp. 1384-8, (2003) (PubMed).

Huang, Fish, Dorfman, Salvatore, Kozakewich, Mandel, Larsen: "A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4457-61, (2002) (PubMed).

Target Details for DIO3

Target: DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))

Alternative Name: DIO3 (DIO3 Products)

Synonyms: 5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody

Gene ID: 29475

Pathways: Hormone Activity