STAT5B antibody (C-Term)

Catalog No. ABIN544535

Product Details anti-STAT5B Antibody

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of STAT5B.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human STAT5B.

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-STAT5B antibody (ABIN544535)

Uddin, Lekmine, Sassano, Rui, Fish, Platanias: "Role of Stat5 in type I interferon-signaling and transcriptional regulation." in: Biochemical and biophysical research communications, Vol. 308, Issue 2, pp. 325-30, (2003) (PubMed).

Zhang, Msc, Moilanen, Lahti, Hämäläinen, Giembycz, Barnes, Lindsay, Kankaanranta: "Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5." in: The Journal of allergy and clinical immunology, Vol. 112, Issue 1, pp. 93-101, (2003) (PubMed).

Xi, Zhang, Gooding, Smithgall, Grandis: "Constitutive activation of Stat5b contributes to carcinogenesis in vivo." in: Cancer research, Vol. 63, Issue 20, pp. 6763-71, (2003) (PubMed).

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5B (STAT5B Products)

Synonyms: STAT5 antibody, stat5 antibody, STAT5A antibody, STAT5B antibody, signal transducer and activator of transcription 5B antibody, signal transducer and activator of transcription 5B S homeolog antibody, Signal transducer and activator of transcription 5B antibody, STAT5B antibody, Stat5b antibody, stat5b.S antibody, LOC490969 antibody, sta5b antibody, LOC100566752 antibody, LOC100052954 antibody

Gene ID: 6777

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation