Calcitonin Receptor antibody (C-Term)

Catalog No. ABIN5514665

Product Details anti-Calcitonin Receptor Antibody

Target: Calcitonin Receptor (CALCR)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RWGRRPSNRS ARAAAAAAEA GDIPIYICHQ EPRNEPANNQ GEESAEIIPL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CALCR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: CALCR (CALCR Products)

Synonyms: CALCR antibody, si:ch211-77k19.2 antibody, calcr antibody, CRT antibody, CT-R antibody, CTR antibody, CTR1 antibody, Clr antibody, Ct-R antibody, calcitonin receptor antibody, CALCR antibody, calcr antibody, Calcr antibody

Background: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.

Alias Symbols: CRT, CTR, CT-R, CTR1

Protein Size: 508

Gene ID: 799

NCBI Accession: NM_001164737, NP_001158209

UniProt: P30988

Pathways: cAMP Metabolic Process