Paxillin antibody (N-Term)

Catalog No. ABIN5515060

Product Details anti-Paxillin Antibody

Target: Paxillin (PXN)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paxillin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VGEEEHVYSF PNKQKSAEPS PTVMSTSLGS NLSELDRLLL ELNAVQHNPP

Characteristics: This is a rabbit polyclonal antibody against PXN. It was validated on Western Blot.

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PXN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Paxillin

Target: Paxillin (PXN)

Alternative Name: PXN (PXN Products)

Synonyms: AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody

Background: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

Protein Interaction Partner: ADAM17, ADAM10, IQGAP1, SUMO1, NEDD8, CHMP5, SEC23B, SEC24D, NAA10, ZYX, PTK2, PTK2B, XPO1, rnf-5, CREB3L2, POLR1D, ASAP1, UBC, RNF5, FN1, DGUOK, AHCY, GART, NUDCD2, DSTN, TLN1, IGBP1, CBL, BCR, CTTN, ITGAV, PARVA, NEDD9, GIT2, PPP2CA, SDC4, NF2, GIT1, GS

Protein Size: 557

Gene ID: 5829

Pathways: MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling