IRF1 antibody (Middle Region)
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- Target See all IRF1 Antibodies
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NFQVSPMPST SEATTDEDEE GKLPEDIMKL LEQSEWQPTN VDGKGYLLNE
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IRF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human IRF1
- Top Product
- Discover our top product IRF1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Alternative Name
- IRF1 (IRF1 Products)
- Synonyms
- irf1 antibody, zgc:136945 antibody, IRF1 antibody, irf11 antibody, zgc:103566 antibody, IRF-1 antibody, MAR antibody, AU020929 antibody, Irf-1 antibody, interferon regulatory factor 1 antibody, interferon regulatory factor 1a antibody, interferon regulatory factor 1b antibody, IRF1 antibody, irf1a antibody, irf1b antibody, Irf1 antibody
- Background
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IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Alias Symbols: IRF1,
Protein Interaction Partner: SUMO2, SUMO3, IRF2, KAT2B, EP300, PRDM1, UBC, BIRC3, MDM2, HIST1H3A, CBL, HSP90AA1, HSPA1A, Tbk1, STUB1, SPI1, QARS, IRF8, CDKN1B, TRIM28, SET, SP2, IRF9, YBX1, NPM1, TRMT2A, HCFC1, SEC63, KEAP1, TRAF3, CREBBP, tat, SMARCA4, STAT1, HMGA1, RELA, NFKB1, KAT
Protein Size: 325 - Gene ID
- 3659
- NCBI Accession
- NM_002198, NP_002189
- UniProt
- P10914
- Pathways
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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