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SREBF chaperone antibody (C-Term)
SCAP
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SREBF chaperone Antibody
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Target
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SREBF chaperone (SCAP)
Binding Specificity
All epitopes for SREBF chaperone antibodies
C-Term
Reactivity
All reactivities for SREBF chaperone antibodies
Human
Host
All hosts for SREBF chaperone antibodies
Rabbit
Clonality
All clonalities for SREBF chaperone antibodies
Polyclonal
Conjugate
All conjugates for SREBF chaperone antibodies
This SREBF chaperone antibody is un-conjugated
Application
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Western Blotting (WB)
Sequence
GPPPPSLFGD QPDLTCLIDT NFSAQPRSSQ PTQPEPRHRA VCGRSRDSPG
Characteristics
This is a rabbit polyclonal antibody against SCAP. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCAP
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SREBF chaperone
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Target
SREBF chaperone (SCAP)
Alternative Name
SCAP (SCAP Products )
Synonyms
9530044G19 antibody, mKIAA0199 antibody, SREBF chaperone antibody, SREBF chaperone S homeolog antibody, SCAP antibody, Scap antibody, scap.S antibody
Background
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alias Symbols: SCAP, KIAA0199, PSEC0227, Protein Interaction Partner: ERLIN2, INSIG1, UBC, INSIG2, SREBF2, SREBF1, RNF139, SEC24B, SCAP, PGRMC1, Protein Size: 1279
Gene ID
22937
NCBI Accession
XP_006713097
UniProt
Q12770
Pathways
SARS-CoV-2 Protein Interactome
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