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LITAF antibody (N-Term)
LITAF
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LITAF Antibody
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Target
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LITAF
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Binding Specificity
All epitopes for LITAF antibodies
N-Term
Reactivity
All reactivities for LITAF antibodies
Human
Host
All hosts for LITAF antibodies
Rabbit
Clonality
All clonalities for LITAF antibodies
Polyclonal
Conjugate
All conjugates for LITAF antibodies
This LITAF antibody is un-conjugated
Application
All applications for LITAF antibodies
Western Blotting (WB)
Sequence
PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN
Characteristics
This is a rabbit polyclonal antibody against LITAF. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human LITAF
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for LITAF
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Target
LITAF
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Alternative Name
LITAF (LITAF Products )
Synonyms
PIG7 antibody, SIMPLE antibody, TP53I7 antibody, EET-1 antibody, Pig7 antibody, TNF-alpha antibody, 3222402J11Rik antibody, C85531 antibody, N4WBP3 antibody, TBX1 antibody, lipopolysaccharide induced TNF factor antibody, lipopolysaccharide-induced TNF factor antibody, LPS-induced TN factor antibody, LITAF antibody, Litaf antibody
Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. Alias Symbols: LITAF, PIG7, SIMPLE, Protein Interaction Partner: REEP6, UBQLN1, STAM2, CALCOCO2, BAG3, HGS, UBC, STAT6, ATXN1, ITCH, TSG101, NEDD4, ELAVL1, RADIL, SMAD2, COMT, Protein Size: 228
Gene ID
9516
Pathways
Cellular Response to Molecule of Bacterial Origin
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