MICU1 antibody (Middle Region)

Catalog No. ABIN5516633

Product Details anti-MICU1 Antibody

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICU1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GMRHRDRPTT GNTLKSGLCS ALTTYFFGAD LKGKLTIKNF LEFQRKLQHD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBARA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Alternative Name: CBARA1 (MICU1 Products)

Synonyms: CALC antibody, CBARA1 antibody, EFHA3 antibody, C730016L05Rik antibody, Calc antibody, Cbara1 antibody, mitochondrial calcium uptake 1 antibody, MICU1 antibody, Micu1 antibody

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Alias Symbols: CALC, EFHA3, MPXPS, CBARA1

Protein Size: 278

Gene ID: 10367

NCBI Accession: NM_001195518, NP_001182447