CLIC5 antibody (Isoform 1)
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- Target See all CLIC5 Antibodies
- CLIC5 (Chloride Intracellular Channel 5 (CLIC5))
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Binding Specificity
- AA 160-173, Isoform 1
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CLIC5 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificity
- This antibody recognizes CLIC5a, a 32 kDa protein which is component of actin complexes. Cross reactivity with CLIC5b was not determined.
- Purification
- Protein-A affinity chromatography (> 95% by SDS-PAGE)
- Immunogen
- KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a
- Clone
- CLIC5-02
- Isotype
- IgG2b
- Top Product
- Discover our top product CLIC5 Primary Antibody
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- Application Notes
- Flow cytometry. Western blot.
- Protocol
- 1. Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. Am J Physiol Renal Physiol. 2010 Jun298(6):F1492-503.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 95 % by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
- Expiry Date
- 12 months
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- Target
- CLIC5 (Chloride Intracellular Channel 5 (CLIC5))
- Alternative Name
- clic5 (CLIC5 Products)
- Synonyms
- MST130 antibody, MSTP130 antibody, 5730531E12Rik antibody, B330005L24 antibody, Gm322 antibody, jbg antibody, clic5 antibody, im:6907594 antibody, zgc:77538 antibody, CLIC5 antibody, zgc:101827 antibody, chloride intracellular channel 5 antibody, chloride intracellular channel 5b antibody, chloride intracellular channel 5a antibody, chloride intracellular channel 5 L homeolog antibody, CLIC5 antibody, Clic5 antibody, clic5b antibody, clic5a antibody, clic5.L antibody
- Background
- CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.
- UniProt
- Q9NZA1
- Pathways
- Sensory Perception of Sound
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