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PRDM16 antibody (AA 779-996)
PRDM16
Reactivity: Human
WB
Host: Mouse
Monoclonal
1740CT793-52-44
unconjugated
Product Details anti-PRDM16 Antibody
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Target
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PRDM16
(PR Domain Containing 16 (PRDM16))
Binding Specificity
All epitopes for PRDM16 antibodies
AA 779-996
Reactivity
All reactivities for PRDM16 antibodies
Human
Host
All hosts for PRDM16 antibodies
Mouse
Clonality
All clonalities for PRDM16 antibodies
Monoclonal
Conjugate
All conjugates for PRDM16 antibodies
This PRDM16 antibody is un-conjugated
Application
All applications for PRDM16 antibodies
Western Blotting (WB)
Purification
Purified
Immunogen
A partial recombinant protein corresponding to amino acids 779-996 from the human protein was used as the immunogen for the PRDM16 antibody.
Clone
1740CT793-52-44
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Western blot: 1:2000-4000
Restrictions
For Research Use only
Handling
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Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PRDM16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for PRDM16
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Target
PRDM16
(PR Domain Containing 16 (PRDM16))
Alternative Name
PRDM16 (PRDM16 Products )
Synonyms
PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody
Background
PR domain zinc finger protein 16 binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
Gene ID
63976
UniProt
Q9HAZ2
Pathways
Stem Cell Maintenance , Brown Fat Cell Differentiation
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