PRDM16 antibody (AA 779-996)

Catalog No. ABIN5647233

Product Details anti-PRDM16 Antibody

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Binding Specificity: AA 779-996

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRDM16 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: A partial recombinant protein corresponding to amino acids 779-996 from the human protein was used as the immunogen for the PRDM16 antibody.

Clone: 1740CT793-52-44

Isotype: IgG1 kappa

Application Details

Application Notes: Western blot: 1:2000-4000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PRDM16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRDM16

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Alternative Name: PRDM16 (PRDM16 Products)

Synonyms: PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody

Background: PR domain zinc finger protein 16 binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Gene ID: 63976

UniProt: Q9HAZ2

Pathways: Stem Cell Maintenance, Brown Fat Cell Differentiation