Recombinant CD11b antibody
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA
- Specificity
- This antibody binds to the MIDAS face of the A domain from integrin CD11b.
- Characteristics
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
- Purification
- Purified antibody.
- Immunogen
- Wild type (WT) recombinant CD11b.
- Clone
- 107
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ITGAM Primary Antibody
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- Application Notes
- he antibody binds specifically to integrin a-M, a protein subunit of the a-M- ß-2 Molecule, which is expressed on the surface of leukocytes. Integrin a-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- Integrin alpha-M (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
- CD11b, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, Neutrophil adherence receptor, complement receptor 3
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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