CDKN2B antibody (C-Term, Isoform 2)

Catalog No. ABIN5688046

Product Details anti-CDKN2B Antibody

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Binding Specificity: C-Term, Isoform 2

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CDKN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody is expected to recognize isoform 2 (NP_511042.1) only.

Purification: p15INK4b isoform 2 Antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: p15INK4b isoform 2 Antibody was raised against synthetic peptide RQGARERGARP found near the C Terminus of p15INK4b.

Application Details

Application Notes: ELISA: antibody detection limit dilution 1:128000. Western Blot: Approx 12+14  kDa bands observed in Human Gastrointestinal cancer lysates (calculated MW of 8.1  kDa according to NP_511042.1). The observed 14  kDa cannot represent isoform 1 and therefore it most likely represents another posttranslational modi

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: p15INK4b is supplied in Tris saline, 0.02 % sodium azide,  pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C. Minimize freezing and thawing.

Target Details for CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Alternative Name: p15INK4b (CDKN2B Products)

Synonyms: p14-INK4b antibody, cdk4l antibody, ink4b antibody, mts2 antibody, p15 antibody, p15ink4b antibody, tp15 antibody, CDK4I antibody, INK4B antibody, MTS2 antibody, P15 antibody, TP15 antibody, p15INK4b antibody, AV083695 antibody, INK4b antibody, p15(INK4b) antibody, CDKN2A antibody, cyclin dependent kinase inhibitor 2B antibody, Cyclin-dependent kinase 4 inhibitor B antibody, cyclin-dependent kinase inhibitor 2B antibody, cyclin-dependent kinase inhibitor 2B L homeolog antibody, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antibody, CDKN2B antibody, cdn2b antibody, cdkn2b antibody, cdkn2b.L antibody, Cdkn2b antibody

Molecular Weight: Approx 12 + 14kDa

Gene ID: 1030

NCBI Accession: NP_004927, NP_511042

UniProt: P42772

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases