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FOXO4 antibody (AA 195-199)
FOXO4
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FOXO4 Antibody
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Target
See all FOXO4 Antibodies
FOXO4
(Forkhead Box O4 (FOXO4))
Binding Specificity
All epitopes for FOXO4 antibodies
AA 195-199
Reactivity
All reactivities for FOXO4 antibodies
Human, Mouse, Rat
Host
All hosts for FOXO4 antibodies
Rabbit
Clonality
All clonalities for FOXO4 antibodies
Polyclonal
Conjugate
All conjugates for FOXO4 antibodies
This FOXO4 antibody is un-conjugated
Application
All applications for FOXO4 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
This antibody detects endogenous level of total AFX protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
AFX (Ab-197) antibody was raised against a peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for FOXO4
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Target
FOXO4
(Forkhead Box O4 (FOXO4))
Alternative Name
AFX (FOXO4 Products )
Synonyms
FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
Background
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
Molecular Weight
65 kDa
Gene ID
4303
NCBI Accession
NP_001164402
UniProt
P98177
Pathways
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Muscle Cell Differentiation
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