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SHP1 antibody (AA 534-538)
PTPN6
Reactivity: Human, Mouse, Rat
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SHP1 Antibody
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Target
See all SHP1 (PTPN6) Antibodies
SHP1 (PTPN6)
(Protein-tyrosine Phosphatase 1C (PTPN6))
Binding Specificity
All epitopes for SHP1 antibodies
AA 534-538
Reactivity
All reactivities for SHP1 antibodies
Human, Mouse, Rat
Host
All hosts for SHP1 antibodies
Rabbit
Clonality
All clonalities for SHP1 antibodies
Polyclonal
Conjugate
All conjugates for SHP1 antibodies
This SHP1 antibody is un-conjugated
Application
All applications for SHP1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total SHP-1 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
SHP-1 (Ab-536) antibody was raised against a peptide sequence around aa.534~538 (S-E-Y-G-N) derived from Human SHP-1.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for SHP1
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Target
SHP1 (PTPN6)
(Protein-tyrosine Phosphatase 1C (PTPN6))
Alternative Name
SHP 1 (PTPN6 Products )
Synonyms
HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody
Background
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
Molecular Weight
68 kDa
Gene ID
5777
NCBI Accession
NP_002822
UniProt
P29350
Pathways
JAK-STAT Signaling , TCR Signaling , TLR Signaling , Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Response to Growth Hormone Stimulus , Regulation of Leukocyte Mediated Immunity , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , BCR Signaling
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