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CDC25C antibody (AA 214-218)
CDC25C
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDC25C Antibody
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Target
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CDC25C
(Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
Binding Specificity
All epitopes for CDC25C antibodies
AA 214-218
Reactivity
All reactivities for CDC25C antibodies
Human
Host
All hosts for CDC25C antibodies
Rabbit
Clonality
All clonalities for CDC25C antibodies
Polyclonal
Conjugate
All conjugates for CDC25C antibodies
This CDC25C antibody is un-conjugated
Application
All applications for CDC25C antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total cdc25C protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
cdc25C (Ab-216) antibody was raised against a peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for CDC25C
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Target
CDC25C
(Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
Alternative Name
cdc25C (CDC25C Products )
Synonyms
CDC25C antibody, cdc25 antibody, xcdc25c antibody, CDC25 antibody, PPP1R60 antibody, Cdc25 antibody, cdc25-3 antibody, xcdc25-3 antibody, cell division cycle 25C antibody, cell division cycle 25C S homeolog antibody, CDC25C antibody, cdc25c antibody, Cdc25c antibody, cdc25c.S antibody
Background
Cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Molecular Weight
60 kDa
Gene ID
995
NCBI Accession
NP_001781
UniProt
P30307
Pathways
Cell Division Cycle , M Phase
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