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beta-2 Microglobulin antibody (C-Term)
B2M
Reactivity: Human
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-beta-2 Microglobulin Antibody
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Target
See all beta-2 Microglobulin (B2M) Antibodies
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Binding Specificity
All epitopes for beta-2 Microglobulin antibodies
C-Term
Reactivity
All reactivities for beta-2 Microglobulin antibodies
Human
Host
All hosts for beta-2 Microglobulin antibodies
Rabbit
Clonality
All clonalities for beta-2 Microglobulin antibodies
Polyclonal
Conjugate
All conjugates for beta-2 Microglobulin antibodies
This beta-2 Microglobulin antibody is un-conjugated
Application
All applications for beta-2 Microglobulin antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
B2M antibody is human reactive.
Purification
B2M Antibody is affinity chromatography purified via peptide column.
Immunogen
B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M. The immunogen is located within the last 50 amino acids of B2M.
Isotype
IgG
Top Product
Discover our top product B2M Primary Antibody
Alternatives
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Application Details
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Application Notes
B2M antibody can be used for detection of B2M by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
B2M Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
B2M antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for beta-2 Microglobulin
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Target
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Alternative Name
B2M (B2M Products )
Synonyms
Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
Background
B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
Molecular Weight
Predicted: 13 kDa Observed: 12 kDa
Gene ID
567
NCBI Accession
NP_004039
UniProt
P61769
Pathways
TCR Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process
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