MBD3 antibody
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- Target See all MBD3 Antibodies
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MBD3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- methyl-CpG binding domain protein 3
- Isotype
- IgG
- Top Product
- Discover our top product MBD3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Y79 cells were subjected to SDS PAGE followed by western blot with FNab05035(MBD3 antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Alternative Name
- MBD3 (MBD3 Products)
- Synonyms
- xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
- Background
- Synonyms: Background:Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
- Molecular Weight
- 33 kDa
- Gene ID
- 53615
- UniProt
- O95983
- Pathways
- Chromatin Binding
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