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SOCS6 antibody
SOCS6
Reactivity: Human, Mouse, Rat
WB, IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SOCS6 Antibody
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Target
See all SOCS6 Antibodies
SOCS6
(Suppressor of Cytokine Signaling 6 (SOCS6))
Reactivity
All reactivities for SOCS6 antibodies
Human, Mouse, Rat
Host
All hosts for SOCS6 antibodies
Rabbit
Clonality
All clonalities for SOCS6 antibodies
Polyclonal
Conjugate
All conjugates for SOCS6 antibodies
This SOCS6 antibody is un-conjugated
Application
All applications for SOCS6 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Immunogen
suppressor of cytokine signaling 6
Isotype
IgG
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Discover our top product SOCS6 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target Details for SOCS6
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Target
SOCS6
(Suppressor of Cytokine Signaling 6 (SOCS6))
Alternative Name
SOCS6 (SOCS6 Products )
Synonyms
CIS-4 antibody, CIS4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, SSI4 antibody, STAI4 antibody, STATI4 antibody, socs6 antibody, MGC81477 antibody, SOCS6 antibody, 1500012M23Rik antibody, 5830401B18Rik antibody, AI447482 antibody, Cis4 antibody, Cish4 antibody, Socs4 antibody, socs6l antibody, zgc:64107 antibody, wu:fb77f06 antibody, suppressor of cytokine signaling 6 antibody, suppressor of cytokine signaling 6 L homeolog antibody, suppressor of cytokine signaling antibody, suppressor of cytokine signaling 6b antibody, SOCS6 antibody, Socs6 antibody, socs6.L antibody, socs6 antibody, socs6b antibody
Background
Synonyms:CIS4, SOCS4 Background:SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Gene ID
9306
UniProt
O14544
Pathways
JAK-STAT Signaling , Carbohydrate Homeostasis
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