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PAG1 antibody
PAG1
Reactivity: Human, Mouse
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PAG1 Antibody
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Target
See all PAG1 Antibodies
PAG1
(phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
Reactivity
All reactivities for PAG1 antibodies
Human, Mouse
Host
All hosts for PAG1 antibodies
Rabbit
Clonality
All clonalities for PAG1 antibodies
Polyclonal
Conjugate
All conjugates for PAG1 antibodies
This PAG1 antibody is un-conjugated
Application
All applications for PAG1 antibodies
Western Blotting (WB), ELISA
Immunogen
phosphoprotein associated with glycosphingolipid microdomains 1
Isotype
IgG
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Discover our top product PAG1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target Details for PAG1
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Target
PAG1
(phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
Alternative Name
PAG1 (PAG1 Products )
Synonyms
Cbp antibody, F730007C19Rik antibody, Pag antibody, CBP antibody, PAG antibody, MGC80192 antibody, phosphoprotein associated with glycosphingolipid microdomains 1 antibody, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 antibody, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 L homeolog antibody, Pag1 antibody, PAG1 antibody, pag1.L antibody, pag1 antibody
Background
Synonyms:CBP, PAG Background:Negatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Gene ID
55824
UniProt
Q9NWQ8
Pathways
p53 Signaling , TCR Signaling , EGFR Signaling Pathway , CXCR4-mediated Signaling Events
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