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GCK antibody
GCK
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GCK Antibody
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Target
See all GCK Antibodies
GCK
(Glucokinase (Hexokinase 4) (GCK))
Reactivity
All reactivities for GCK antibodies
Human, Mouse, Rat
Host
All hosts for GCK antibodies
Rabbit
Clonality
All clonalities for GCK antibodies
Polyclonal
Conjugate
All conjugates for GCK antibodies
This GCK antibody is un-conjugated
Application
All applications for GCK antibodies
Western Blotting (WB), ELISA
Immunogen
glucokinase (hexokinase 4)
Isotype
IgG
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Discover our top product GCK Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target Details for GCK
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Target
GCK
(Glucokinase (Hexokinase 4) (GCK))
Alternative Name
GCK (GCK Products )
Synonyms
FGQTL3 antibody, GK antibody, GLK antibody, HHF3 antibody, HK4 antibody, HKIV antibody, HXKP antibody, LGLK antibody, MODY2 antibody, Gk antibody, Gls006 antibody, GCK antibody, BA4487 antibody, glk antibody, hk4 antibody, hhf3 antibody, hkiv antibody, hxkp antibody, gck-A antibody, mody2 antibody, glucokinase antibody, GLUKA antibody, RNGK2 antibody, glucokinase antibody, glucokinase (hexokinase 4) L homeolog antibody, glucokinase (hexokinase 4) antibody, GCK antibody, Gck antibody, glcK antibody, Bphyt_1025 antibody, Halhy_6548 antibody, gk antibody, gck.L antibody, gck antibody
Background
Synonyms: Background:Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Molecular Weight
50-52 kDa
Gene ID
2645
UniProt
P35557
Pathways
MAPK Signaling , Positive Regulation of Peptide Hormone Secretion , Carbohydrate Homeostasis , Cellular Glucan Metabolic Process , Regulation of Carbohydrate Metabolic Process
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