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IRS1 antibody (pTyr896)
IRS1
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IRS1 Antibody
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Target
See all IRS1 Antibodies
IRS1
(Insulin Receptor Substrate 1 (IRS1))
Binding Specificity
All epitopes for IRS1 antibodies
pTyr896
Reactivity
All reactivities for IRS1 antibodies
Human, Mouse, Rat
Host
All hosts for IRS1 antibodies
Rabbit
Clonality
All clonalities for IRS1 antibodies
Polyclonal
Conjugate
All conjugates for IRS1 antibodies
This IRS1 antibody is un-conjugated
Application
All applications for IRS1 antibodies
Western Blotting (WB), ELISA
Specificity
HIRS 1,HIRS1,Insulin receptor substrate 1,IRS 1,IRS-1,IRS1,IRS1,OTTHUMP00000164234
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896
Isotype
IgG
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Discover our top product IRS1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, ELISA 1:40000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for IRS1
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Target
IRS1
(Insulin Receptor Substrate 1 (IRS1))
Alternative Name
IRS1 (IRS1 Products )
Synonyms
HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Molecular Weight
132kDa
Gene ID
3667
UniProt
P35568
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Hormone Transport , Negative Regulation of Hormone Secretion , Response to Growth Hormone Stimulus , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process
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