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Caspase 9 antibody (Thr125)
CASP9
Reactivity: Human, Mouse, Rat
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Caspase 9 Antibody
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Target
See all Caspase 9 (CASP9) Antibodies
Caspase 9 (CASP9)
(Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
Binding Specificity
All epitopes for Caspase 9 antibodies
Thr125
Reactivity
All reactivities for Caspase 9 antibodies
Human, Mouse, Rat
Host
All hosts for Caspase 9 antibodies
Rabbit
Clonality
All clonalities for Caspase 9 antibodies
Polyclonal
Conjugate
All conjugates for Caspase 9 antibodies
This Caspase 9 antibody is un-conjugated
Application
All applications for Caspase 9 antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASP9,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,PPP1R56,protein phosphatase 1,regulatory subunit 56,RNCASP9
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.
Isotype
IgG
Top Product
Discover our top product CASP9 Primary Antibody
Alternatives
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anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 11-120) antibody
CASP9
Reactivity: Human, Mouse, Rat, Chicken, Dog, Rabbit
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Caspase 9
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Target
Caspase 9 (CASP9)
(Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
Alternative Name
CASP9 (CASP9 Products )
Synonyms
CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Molecular Weight
46kDa
Gene ID
842
UniProt
P55211
Pathways
MAPK Signaling , RTK Signaling , Apoptosis , Caspase Cascade in Apoptosis , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Endopeptidase Activity
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