JUP antibody

Catalog No. ABIN5963656

Product Details anti-JUP Antibody

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human JUP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Catenin gamma (JUP Products)

Synonyms: ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody

Background:

Synonyms: ARVD 12,ARVD12,Catenin (cadherin associated protein),gamma 80  kDa,catenin (cadherin-associated protein) gamma (80kD),Catenin gamma,CTNNG,Desmoplakin 3,Desmoplakin III,Desmoplakin-3,Desmoplakin3,DesmoplakinIII,DP 3,DP III,DP3,DPIII,gamma catenin,Junction plakoglobin,JUP,OTTHUMP00000164732,OTTHUMP00000164735,OTTHUMP00000164738,PDGB,PKGB,PLAK,PLAKOGLOBIN

Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.

Molecular Weight:

Observed_MW: 82kDa

Calculated_MW: 81kDa

Gene ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location