CDKN2C antibody
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- Target See all CDKN2C Antibodies
- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDKN2C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CDKN2C/p18-INK4C
- Isotype
- IgG
- Top Product
- Discover our top product CDKN2C Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
- Alternative Name
- CDKN2C (CDKN2C Products)
- Synonyms
- CDKN2C antibody, p18 antibody, ink4c antibody, p18-ink4c antibody, INK4C antibody, p18-INK4C antibody, C77269 antibody, INK4c antibody, INK4d antibody, p18INK4c antibody, cyclin dependent kinase inhibitor 2C antibody, cyclin-dependent kinase inhibitor 2C antibody, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) antibody, CDKN2C antibody, cdkn2c antibody, Cdkn2c antibody
- Background
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.,CDKN2C,INK4C,p18,p18-INK4C,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,CDKN2C
- Molecular Weight
- 18 kDa
- Gene ID
- 1031
- UniProt
- P42773
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
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