CDKN2B antibody (AA 1-138)
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- Target See all CDKN2B Antibodies
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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Binding Specificity
- AA 1-138
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDKN2B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAGADP NGVNRFGRRA IQVMMMGSAR VAELLLLHGA EPNCADPATL TRPVHDAARE GFLDTLVVLH RAGARLDVRD AWGRLPVDLA EERGHRDVAG YLRTATGD
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human CDKN2B (NP_004927.2).
- Isotype
- IgG
- Top Product
- Discover our top product CDKN2B Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
- Alternative Name
- CDKN2B (CDKN2B Products)
- Synonyms
- p14-INK4b antibody, cdk4l antibody, ink4b antibody, mts2 antibody, p15 antibody, p15ink4b antibody, tp15 antibody, CDK4I antibody, INK4B antibody, MTS2 antibody, P15 antibody, TP15 antibody, p15INK4b antibody, AV083695 antibody, INK4b antibody, p15(INK4b) antibody, CDKN2A antibody, cyclin dependent kinase inhibitor 2B antibody, Cyclin-dependent kinase 4 inhibitor B antibody, cyclin-dependent kinase inhibitor 2B antibody, cyclin-dependent kinase inhibitor 2B L homeolog antibody, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antibody, CDKN2B antibody, cdn2b antibody, cdkn2b antibody, cdkn2b.L antibody, Cdkn2b antibody
- Background
- This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.,CDKN2B,CDK4I,INK4B,MTS2,P15,TP15,p15INK4b,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Stem Cells,CDKN2B
- Molecular Weight
- 8 kDa/14 kDa
- Gene ID
- 1030
- UniProt
- P42772
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
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