DAZ2 antibody (AA 1-200)

Catalog No. ABIN6139413

Product Details anti-DAZ2 Antibody

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSAANPETPN STISREASTQ SSSAAASQGW VLPEGKIVPN TVFVGGIDAR MDETEIGSCF GRYGSVKEVK IITNRTGVSK GYGFVSFVND VDVQKIVGSQ IHFHGKKLKL GPAIRKQKLC ARHVQPRPLV VNPPPPPQFQ NVWRNPNTET YLQPQITPNP VTQHVQAYSA YPHSPGQVIT GCQLLVYNYQ EYPTYPDSAF

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DAZ2 (NP_001005785.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Alternative Name: DAZ2 (DAZ2 Products)

Synonyms: pDP1678 antibody, DAZ2 antibody, deleted in azoospermia 2 antibody, deleted in azoospermia protein 2 antibody, DAZ2 antibody, LOC738583 antibody

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.,DAZ2,pDP1678,DAZ2

Molecular Weight: 41 kDa/60 kDa/63 kDa

Gene ID: 57055

UniProt: Q13117