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PLK1 antibody
PLK1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PLK1 Antibody
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Target
See all PLK1 Antibodies
PLK1
(Polo-Like Kinase 1 (PLK1))
Reactivity
All reactivities for PLK1 antibodies
Human
Host
All hosts for PLK1 antibodies
Rabbit
Clonality
All clonalities for PLK1 antibodies
Polyclonal
Conjugate
All conjugates for PLK1 antibodies
This PLK1 antibody is un-conjugated
Application
All applications for PLK1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects PLK1.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Immunoaffinity Chromatography
Immunogen
PLK1 antibody was raised against recombinant protein
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
0.1 M Tris-glycine, pH 7, 10 % Glycerol, 0.01 % Thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C. Dilute only prior to immediate use.
Target Details for PLK1
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Target
PLK1
(Polo-Like Kinase 1 (PLK1))
Alternative Name
PLK1 (PLK1 Products )
Synonyms
PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
Background
PLK, a Polo type protein kinase, has been shown to function in mitosis. The mRNA is absent or expressed at very low levels during the G1 phase, begins to reaccumulate during the S phase, and reaches maximal levels during the G2/M phase. PLK1 may participate in targeting MPF to the nucleus during prophase and in regulating mitotic spindle function. These functions, in addition to its expression in proliferating cells, suggest that PLK1 has a role in cancer progression.Synonyms: PLK-1, Polo-like kinase 1, STPK13, Serine/threonine-protein kinase PLK1
Gene ID
5347
NCBI Accession
NP_005021
UniProt
P53350
Pathways
Cell Division Cycle , M Phase
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