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XRCC3 antibody (AA 202-296)
XRCC3
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-XRCC3 Antibody
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Target
See all XRCC3 Antibodies
XRCC3
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
Binding Specificity
All epitopes for XRCC3 antibodies
AA 202-296
Reactivity
All reactivities for XRCC3 antibodies
Human
Host
All hosts for XRCC3 antibodies
Rabbit
Clonality
All clonalities for XRCC3 antibodies
Polyclonal
Conjugate
All conjugates for XRCC3 antibodies
This XRCC3 antibody is un-conjugated
Application
All applications for XRCC3 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Specificity
Recognizes XRCC3. Cellular Localization: Nucleus.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Antigen-Affinity Chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 202 and 296 of Human XRCC3
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) and 0.01 % Thimerosal as preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at -20 °C.
Target Details for XRCC3
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Target
XRCC3
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
Alternative Name
XRCC3 (XRCC3 Products )
Synonyms
CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
Background
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identifiedSynonyms: DNA repair protein XRCC3, X-ray repair cross-complementing protein 3
Molecular Weight
38 kDa
Gene ID
7517, 9606
UniProt
O43542
Pathways
DNA Damage Repair
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