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NEDD8 antibody (AA 1-81)
NEDD8
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NEDD8 Antibody
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Target
See all NEDD8 Antibodies
NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Binding Specificity
All epitopes for NEDD8 antibodies
AA 1-81
Reactivity
All reactivities for NEDD8 antibodies
Human
Host
All hosts for NEDD8 antibodies
Rabbit
Clonality
All clonalities for NEDD8 antibodies
Polyclonal
Conjugate
All conjugates for NEDD8 antibodies
This NEDD8 antibody is un-conjugated
Application
All applications for NEDD8 antibodies
Western Blotting (WB)
Sequence
MLIKVKTLTG KEIEIDIEPT DKVERIKERV EEKEGIPPQQ QRLIYSGKQM NDEKTAADYK ILGGSVLHLV LALRGGGGLR Q
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-81 of human NEDD8 (NP_006147.1).
Isotype
IgG
Top Product
Discover our top product NEDD8 Primary Antibody
Alternatives
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibody
NEDD8
Reactivity: Human, Mouse, Rat, Monkey, Cow, Xenopus laevis
WB, IHC, IHC (p), IF, FACS, IP
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NEDD8
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Target
NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Alternative Name
NEDD8 (NEDD8 Products )
Synonyms
NEDD-8 antibody, Rub1 antibody, CG10679 antibody, Dmel\\CG10679 antibody, NEDD8 antibody, dNEDD8 antibody, nedd8 antibody, ubiquitin antibody, si:zc14a17.5 antibody, GB17785 antibody, DDBDRAFT_0218116 antibody, DDBDRAFT_0238041 antibody, DDB_0218116 antibody, DDB_0238041 antibody, nedd8.S antibody, neural precursor cell expressed, developmentally down-regulated 8 antibody, neural precursor cell expressed, developmentally down-regulated gene 8 antibody, CG10679 gene product from transcript CG10679-RB antibody, Nedd8 antibody, ubiquitin-like protein Nedd8 antibody, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antibody, NEDD8 antibody, Nedd8 antibody, nedd8 antibody, nedd8.L antibody
Background
Nedd8 is an 81 amino acid Ub-like protein. It is conjugated to protein substrates in much the same way as Ub, using the E1, E2, E3 cascade. The specific E1 used is a heterodimer of APPBP1/UBA3. Two E2s have been discovered to follow called Ubc12 and Ube2F. Neddylation causes conformational change of the Cullin protein in the E3 called cullin-RING ligases (CRLs), which enhances the E3 Ub ligase activity of CRLs.,NEDD8,NEDD-8,Cell Biology & Developmental Biology,Ubiquitin,NEDD8
Molecular Weight
9 kDa
Gene ID
4738
UniProt
Q15843
Pathways
Ubiquitin Proteasome Pathway
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