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TNFSF18 antibody

TNFSF18 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256856
  • Target See all TNFSF18 Antibodies
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    Reactivity
    • 60
    • 29
    • 5
    • 2
    • 2
    • 1
    Human
    Host
    • 51
    • 10
    • 6
    Rabbit
    Clonality
    • 50
    • 15
    • 1
    Polyclonal
    Conjugate
    • 35
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFSF18 antibody is un-conjugated
    Application
    • 53
    • 32
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    TNF18 antibody detects endogenous levels of total TNF18
    Cross-Reactivity
    Human
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    Alternative Name
    TNF18 (TNFSF18 Products)
    Synonyms
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    Background

    Description: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).

    Gene: TNFSF18

    Molecular Weight
    72 kDa
    Gene ID
    8995
    UniProt
    Q9UNG2
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