CACNA1D antibody (Internal Region)

Catalog No. ABIN6260394

Product Details anti-CACNA1D Antibody

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Binding Specificity: Internal Region

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CACNA1D Antibody detects endogenous levels of total CACNA1D.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CACNA1D, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Alternative Name: CACNA1D (CACNA1D Products)

Synonyms: cacna1d antibody, cav1.3a antibody, isl antibody, si:dz136d19.3 antibody, si:dz223c6.1 antibody, ca(v)1.3 antibody, cav1.3 antibody, CACH3 antibody, CACN4 antibody, CACNL1A2 antibody, CCHL1A2 antibody, Cav1.3 antibody, SANDD antibody, 8430418G19Rik antibody, C79217 antibody, Cacnl1a2 antibody, Cchl1a antibody, Cchl1a2 antibody, D-LTCC antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antibody, calcium voltage-gated channel subunit alpha1 D antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antibody, cacna1da antibody, CACNA1D antibody, cacna1d antibody, cacna1d.L antibody, Cacna1d antibody

Background:

Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

Gene: CACNA1D

Molecular Weight: 245 kDa

Gene ID: 776

UniProt: Q01668

Pathways: Sensory Perception of Sound