PPARA antibody (Ser21)
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- Target See all PPARA Antibodies
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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Binding Specificity
- AA 1-80, Ser21
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPARA antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purpose
- PPAR-α is a protein encoded by the PPARA gene which is approximately 52,2 kDa. PPAR-α is localised to the nucleus. It is involved in regulation of cholesterol biosynthesis by SREBP, gene expression and metabolism. It is a ligand-activated transcription factor that heterodimerize with the retinoic X receptor to regulate gene expression. It is also a key regulator of lipid metabolism. PPAR-α is expressed in skeletal muscle, liver, heart and the kidney. Mutations in the PPARA gene may result in fatty liver disease and Tularemia. STJ95200 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PPAR-α protein.
- Specificity
- PPAR-α Polyclonal Antibody detects endogenous levels of PPAR-α protein.
- Characteristics
- Rabbit polyclonal to PPAR-α.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human PPAR-alpha around the non-phosphorylation site of S21.
- Isotype
- IgG
- Top Product
- Discover our top product PPARA Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000 - Comment
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Skeletal muscle, liver, heart and kidney.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- Alternative Name
- PPAR-alpha (PPARA Products)
- Synonyms
- NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, LOC100136415 antibody, PPARALPHA antibody, nr1c1 antibody, xPPARalpha antibody, xppara antibody, 4933429D07Rik antibody, AW742785 antibody, Nr1c1 antibody, PPAR-alpha antibody, Ppar antibody, peroxisome proliferator activated receptor alpha antibody, peroxisome proliferator-activated receptor alpha antibody, peroxisome proliferator activated receptor alpha L homeolog antibody, PPARA antibody, LOC100136415 antibody, ppara.L antibody, Ppara antibody, ppara antibody
- Molecular Weight
- 52 kDa
- Gene ID
- 5465
- UniProt
- Q07869
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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