Histone 3 antibody (Lys23)
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- Target See all Histone 3 (H3) Antibodies
- Histone 3 (H3)
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Binding Specificity
- AA 10-90, Lys23
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Histone 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA
- Purpose
- Histone H3 is a protein encoded by the HIST3H3 gene which is approximately 15,5 kDa. Histone H3 is localised to the nucleus and chromosome. It is involved in the DNA double-strand break repair and mitotic cell cycle. This protein falls under the histone family protein. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Histone H3 is expressed in the testicular cells. STJ93530 was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Histone H3 (Phospho-Try41) protein.
- Specificity
- Histone H3 Polyclonal Antibody detects endogenous levels of Histone H3 protein.
- Characteristics
- Rabbit polyclonal to Histone H3.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human Histone H3 around the non-acetylation site of K23
- Isotype
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- Histone 3 (H3)
- Alternative Name
- Histone H3 (H3 Products)
- Synonyms
- H-3 antibody, histocompatibility 3 antibody, H3 antibody
- Molecular Weight
- 17 kDa
- Gene ID
- 8350
- UniProt
- P68431
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