RUNX2 antibody (Internal Region)
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- Target See all RUNX2 Antibodies
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Binding Specificity
- AA 191-240, Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RUNX2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- RUNX2 is a protein encoded by the RUNX2 gene which is approximately 56,6 kDa. RUNX2 is localised to the nucleus. It is involved in gene expression, transcriptional misregulation in cancer, the dendritic cell developmental lineage pathway and the notch signalling pathway. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. RUNX2 is specifically expressed in osteoblasts. Mutations in the RUNX2 gene may result in cleidocranial dysplasia. STJ96721 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of RUNX2 protein.
- Specificity
- RUNX2 Polyclonal Antibody detects endogenous levels of RUNX2 protein.
- Characteristics
- Rabbit polyclonal to RUNX2.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human RUNX2.
- Isotype
- IgG
- Top Product
- Discover our top product RUNX2 Primary Antibody
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- Application Notes
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WB 1:500-1:2000
ELISA 1:20000 - Comment
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Specifically expressed in osteoblasts.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Alternative Name
- RUNX2 (RUNX2 Products)
- Synonyms
- AML3 antibody, CBF-alpha-1 antibody, CBFA1 antibody, CCD antibody, CCD1 antibody, CLCD antibody, OSF-2 antibody, OSF2 antibody, PEA2aA antibody, PEBP2aA antibody, Cbf antibody, Cbfa-1 antibody, Cbfa1 antibody, LS3 antibody, Osf2 antibody, Pebp2a1 antibody, Pebpa2a antibody, runx2 antibody, RUNX2 antibody, ccd antibody, aml3 antibody, ccd1 antibody, osf2 antibody, cbfa1 antibody, pea2aa antibody, pebp2a1 antibody, pebp2a2 antibody, pebp2aa antibody, pebp2aa1 antibody, runt related transcription factor 2 antibody, runt-related transcription factor 2a antibody, runt-related transcription factor 2 antibody, runt related transcription factor 2 L homeolog antibody, RUNX2 antibody, runx2a antibody, Runx2 antibody, runx2 antibody, LOC703331 antibody, LOC100549663 antibody, runx2.L antibody
- Molecular Weight
- 56 kDa
- Gene ID
- 860
- UniProt
- Q13950
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