JAG1 antibody
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- Target See all JAG1 Antibodies
- JAG1 (Jagged 1 (JAG1))
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JAG1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human JAG1
- Isotype
- IgG
- Top Product
- Discover our top product JAG1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Widely expressed in adult and fetal tissues, In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia, Expression is up-regulated in cervical squamous cell carcinoma, Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- JAG1 (Jagged 1 (JAG1))
- Alternative Name
- JAG1 (JAG1 Products)
- Synonyms
- AGS antibody, AHD antibody, AWS antibody, CD339 antibody, HJ1 antibody, JAGL1 antibody, ABE2 antibody, Gsfabe2 antibody, Htu antibody, Ozz antibody, Ser-1 antibody, JAG1 antibody, jag3 antibody, cb243 antibody, jag1 antibody, sb:cb243 antibody, serrateC antibody, jagged1 antibody, serrate antibody, serrate-1 antibody, x-serrate-1 antibody, jagged 1 antibody, jagged 1b antibody, jagged 1a antibody, jagged 1 L homeolog antibody, JAG1 antibody, Jag1 antibody, jag1 antibody, jag1b antibody, jag1a antibody, jag1.L antibody
- Background
- The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
- Molecular Weight
- 133.799 kDa
- Gene ID
- 182
- UniProt
- P78504
- Pathways
- Notch Signaling, Stem Cell Maintenance
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