Nuclear Antigen (IPO-38) antibody

Details for Product No. ABIN6297659
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
26
19
17
Host
Mouse
27
Clonality
Monoclonal
Application
Immunohistochemistry (IHC)
23
21
16
10
4
4
3
3
2
1
Options
Purpose Mouse anti-Human/Mouse/Rat IPO-38 Antibody (Proliferation Marker) [IHC only]
Immunogen Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO-38 antibody.
Specificity Nuclear
Purification Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO-38 antibody.
Antigen
Alternative Name IPO38
Background

Target Description: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO38 may be a useful marker of cell proliferation during monitoring of tumor progression.

Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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