CPT1A antibody

Catalog No. ABIN6569826

Product Details anti-CPT1A Antibody

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human CPT1A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CPT1A

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Alternative Name: CPT1A (CPT1A Products)

Synonyms: MGC53498 antibody, CPT1 antibody, CPT1-L antibody, L-CPT1 antibody, L-CPTI antibody, si:dkey-56p7.8 antibody, C730027G07 antibody, CPTI antibody, Cpt1 antibody, CPT-Ia antibody, carnitine palmitoyltransferase 1A (liver) L homeolog antibody, carnitine palmitoyltransferase 1A antibody, carnitine palmitoyltransferase 1A (liver) antibody, carnitine palmitoyltransferase 1Aa (liver) antibody, carnitine palmitoyltransferase 1a, liver antibody, cpt1a.L antibody, CPT1A antibody, cpt1a antibody, cpt1aa antibody, Cpt1a antibody

Background:

Synonyms: Carnitine O palmitoyltransferase 1 liver isoform,Carnitine O palmitoyltransferase I,Carnitine O palmitoyltransferase I liver isoform,Carnitine O-palmitoyltransferase 1,Carnitine O-palmitoyltransferase I,Carnitine palmitoyltransferase 1A (liver),Carnitine palmitoyltransferase 1A,Carnitine palmitoyltransferase I,Carnitine palmitoyltransferase I liver,CPT 1,CPT I,CPT1,CPT1 L,CPT1-L,Cpt1a,CPT1A,CPTI,CPTI-L,L CPT1,liver isoform

Background: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 86kDa/88kDa

Gene ID: 1374

UniProt: P50416

Pathways: AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process